Karystos is the easiest and most direct destination from Athens. You can come in several ways.
1. From the port of Rafina to Marmari in about 1 hour, with many daily itineraries. From Marmari in 10 minutes drive you will be in Karystos from a comfortable and new road that connects the two cities.
2. By road from Chalkida in about 2.5 hours.
3. From the port of Ag. Marinas for Nea Styra in about 45 minutes, with very frequent daily itineraries. From N. Styra in about 50 minutes you will be in Karystos.